Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0119PFAM: ribulose bisphosphate carboxylase large chain; Ribulose bisphosphate carboxylase, large subunit- like; KEGG: afe:Lferr_1389 ribulose-bisphosphate carboxylase; Belongs to the RuBisCO large chain family. (473 aa)    
Predicted Functional Partners:
Afer_0120
PFAM: ribulose bisphosphate carboxylase small chain; KEGG: afe:Lferr_1388 ribulose-bisphosphate carboxylase.
 
 0.999
Afer_0167
PFAM: phosphoribulokinase/uridine kinase; KEGG: gvi:glr4424 phosphoribulokinase.
 
  
 0.951
pgk
PFAM: phosphoglycerate kinase; KEGG: rxy:Rxyl_2004 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 0.909
Afer_0122
TIGRFAM: carboxysome shell carbonic anhydrase; KEGG: afe:Lferr_1386 carboxysome shell carbonic anhydrase.
 
 
 
 0.907
Afer_1075
KEGG: fra:Francci3_1316 hypothetical protein.
    
 
 0.856
Afer_1874
PFAM: class II aldolase/adducin family protein; KEGG: sth:STH188 sugar isomerase.
  
  
 0.687
Afer_0121
KEGG: afe:Lferr_1387 carboxysome structural protein CsoS2.
 
   
 0.666
rplW
Ribosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
      
 0.659
Afer_1736
PFAM: heat shock protein Hsp20; KEGG: rha:RHA1_ro08348 heat shock protein (18 kDa antigen-like protein); Belongs to the small heat shock protein (HSP20) family.
      
 0.647
Afer_0723
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.611
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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