Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rlmNRadical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (353 aa)    
Predicted Functional Partners:
miaB
RNA modification enzyme, MiaB family; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
 
  
 0.813
Afer_1290
KEGG: ace:Acel_0781 coproporphyrinogen III oxidase, anaerobic; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB.
 
   
 0.654
Afer_0165
KEGG: afw:Anae109_0447 ribulose-phosphate 3- epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
  
 0.615
Afer_0166
TIGRFAM: transketolase; fructose-1,6- bisphosphatase, class II; PFAM: GlpX family protein; Transketolase domain protein; Transketolase central region; KEGG: ttj:TTHA0108 transketolase; Belongs to the transketolase family.
 
   
 0.597
Afer_1687
Methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: nca:Noca_2442 methionyl-tRNA formyltransferase.
  
    0.595
Afer_1685
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.568
nusB
NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
  
 0.559
Afer_0167
PFAM: phosphoribulokinase/uridine kinase; KEGG: gvi:glr4424 phosphoribulokinase.
  
    0.541
Afer_0163
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: lbf:LBF_2704 NADH dehydrogenase.
       0.535
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
 
 
 
 0.511
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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