Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0167PFAM: phosphoribulokinase/uridine kinase; KEGG: gvi:glr4424 phosphoribulokinase. (322 aa)    
Predicted Functional Partners:
Afer_0165
KEGG: afw:Anae109_0447 ribulose-phosphate 3- epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 
 0.980
Afer_0119
PFAM: ribulose bisphosphate carboxylase large chain; Ribulose bisphosphate carboxylase, large subunit- like; KEGG: afe:Lferr_1389 ribulose-bisphosphate carboxylase; Belongs to the RuBisCO large chain family.
 
  
 0.951
Afer_0120
PFAM: ribulose bisphosphate carboxylase small chain; KEGG: afe:Lferr_1388 ribulose-bisphosphate carboxylase.
 
  
 0.940
Afer_0166
TIGRFAM: transketolase; fructose-1,6- bisphosphatase, class II; PFAM: GlpX family protein; Transketolase domain protein; Transketolase central region; KEGG: ttj:TTHA0108 transketolase; Belongs to the transketolase family.
 
   
 0.908
Afer_1196
KEGG: csc:Csac_1200 RpiB/LacA/LacB family sugar- phosphate isomerase; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase.
    
  0.901
Afer_0849
KEGG: kra:Krad_2931 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.835
Afer_1396
PFAM: helicase domain protein; SNF2-related protein; SMART: helicase domain protein; DEAD-like helicases; KEGG: cte:CT0906 DNA-dependent ATPase, SNF2 family protein.
  
 0.714
Afer_0080
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: nca:Noca_1946 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
   
  0.605
Afer_1530
TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; KEGG: fal:FRAAL5848 D-3-phosphoglycerate dehydrogenase.
   
  0.605
Afer_0258
KEGG: cef:CE1107 hypothetical protein.
    
  0.577
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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