Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Afer_0169KEGG: sgr:SGR_2421 LacI family transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI. (377 aa)    
Predicted Functional Partners:
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
    
 
 0.886
Afer_0170
Xylan 1,4-beta-xylosidase; PFAM: glycoside hydrolase family 39; KEGG: xca:xccb100_4166 exported xylan 1,4-beta- xylosidase.
 
     0.815
Afer_0993
Monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; KEGG: rxy:Rxyl_0947 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.646
Afer_0994
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: acr:Acry_1366 periplasmic binding protein/LacI transcriptional regulator.
 
  
 0.624
Afer_1409
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sgr:SGR_1276 GntR family transcriptional regulator.
  
   
 0.607
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
    
   0.566
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.566
Afer_0171
PFAM: extracellular solute-binding protein family 5; KEGG: lxx:Lxx23050 ABC transporter, substrate binding protein.
  
    0.488
pheT
KEGG: ade:Adeh_1971 phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
    
   0.487
Afer_1731
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: kra:Krad_2441 diguanylate phosphodiesterase.
 
      0.483
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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