Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Afer_0182KEGG: dge:Dgeo_2370 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein. (323 aa)    
Predicted Functional Partners:
Afer_1401
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: azo:azo1486 conserved hypothetical signaling protein.
 
  
 0.830
Afer_1402
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: fal:FRAAL5844 hypothetical protein.
 
  
 0.830
Afer_1469
KEGG: eba:ebA6041 signal transducer protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
  
 0.830
Afer_1731
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: kra:Krad_2441 diguanylate phosphodiesterase.
 
  
 0.830
Afer_0022
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: bln:Blon_0041 hypothetical protein.
 
  
 0.828
Afer_1101
KEGG: saq:Sare_1110 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: GGDEF domain containing protein; EAL domain protein.
 
 
 0.808
Afer_1470
Diguanylate cyclase; KEGG: cti:RALTA_B0100 putative diguanylate cyclase (GGDEAF) and C-di-GMP phosphodiesterase (EAL domain) with CHASE and PAS domains; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
  
     0.775
Afer_0180
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; KEGG: mva:Mvan_1358 two component LuxR family transcriptional regulator.
  
  
 0.633
Afer_0178
Hypothetical protein.
       0.613
Afer_0179
PFAM: thiamineS protein; KEGG: afw:Anae109_1160 molybdopterin converting factor, subunit 1.
       0.613
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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