STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0194PFAM: ATP-dependent Clp protease adaptor protein ClpS; KEGG: rha:RHA1_ro01441 ATP-dependent Clp protease adaptor protein ClpS; Belongs to the ClpS family. (96 aa)    
Predicted Functional Partners:
Afer_1903
PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: fal:FRAAL6680 ATP-dependent protease, HSP 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.898
Afer_1964
ATP-dependent chaperone ClpB; KEGG: nfa:nfa54020 putative Clp protease ATP- binding subunit; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.898
Afer_0195
Hypothetical protein.
       0.783
Afer_0193
PFAM: cytochrome oxidase assembly; KEGG: fra:Francci3_1653 cytochrome oxidase assembly.
 
     0.717
whiB-2
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.679
Afer_0835
KEGG: saq:Sare_3891 hypothetical protein.
 
     0.656
whiB
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.616
mshD
Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
     0.615
Afer_1609
PFAM: LmbE family protein; KEGG: sen:SACE_0909 N- acetylglucosaminylphosphatidylinositol deacetylase.
  
     0.603
Afer_0192
PFAM: ABC-2 type transporter; KEGG: fre:Franean1_2079 ABC-2 type transporter.
 
     0.597
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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