STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0199Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: fra:Francci3_2661 ferric uptake regulator family protein; Belongs to the Fur family. (150 aa)    
Predicted Functional Partners:
Afer_0200
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: mab:MAB_4047c sensory transduction protein RegX3.
  
  
 0.808
Afer_0201
Histidine kinase; KEGG: tfu:Tfu_2909 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
     
 0.807
Afer_0294
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: nfa:nfa3250 putative ferric uptake regulator; Belongs to the Fur family.
  
     0.763
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.720
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
     
 0.587
Afer_0346
KEGG: saq:Sare_3145 transcriptional regulator, TrmB.
  
    0.586
Afer_0859
Peroxidase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: xau:Xaut_2363 peroxidase.
  
  
 0.574
Afer_0202
KEGG: fra:Francci3_0038 hypothetical protein.
       0.542
Afer_0206
KEGG: fre:Franean1_1381 type IV secretory pathway VirD4 protein-like protein.
  
    0.536
Afer_0203
Hypothetical protein; KEGG: sgr:SGR_3918 putative integral membrane protein.
       0.535
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.