Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_0206KEGG: fre:Franean1_1381 type IV secretory pathway VirD4 protein-like protein. (386 aa)    
Predicted Functional Partners:
Afer_0205
SMART: AAA ATPase; KEGG: sco:SCO6878 ATP-binding protein.
 
  
 0.935
Afer_0204
KEGG: fre:Franean1_1340 hypothetical protein.
     
 0.792
Afer_0202
KEGG: fra:Francci3_0038 hypothetical protein.
       0.786
Afer_0203
Hypothetical protein; KEGG: sgr:SGR_3918 putative integral membrane protein.
       0.774
Afer_0299
KEGG: cyt:cce_4767 hypothetical protein.
 
    0.718
flgK
TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: ace:Acel_0832 flagellar hook-associated protein FlgK.
       0.692
Afer_0209
KEGG: ace:Acel_0831 flagellar hook-associated protein 3.
       0.687
Afer_0576
PFAM: TrwC relaxase; KEGG: fal:FRAAL6333 putative conjugal transfer protein TraA.
 
   
 0.686
Afer_0207
Hypothetical protein.
       0.671
Afer_0114
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
     0.584
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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