STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0219KEGG: kra:Krad_0325 response regulator receiver protein. (166 aa)    
Predicted Functional Partners:
Afer_0217
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: kra:Krad_0325 response regulator receiver protein.
       0.809
Afer_0220
PFAM: glycosyl transferase family 2; KEGG: ank:AnaeK_2521 glycosyl transferase family 2.
       0.776
Afer_0218
Hypothetical protein; KEGG: bvi:Bcep1808_5226 protease Do.
       0.773
Afer_0214
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
       0.636
Afer_0215
KEGG: bbt:BBta_0527 MCP methyltransferase, CheR- type; PFAM: MCP methyltransferase CheR-type; SMART: MCP methyltransferase CheR-type.
       0.636
Afer_0213
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: kra:Krad_0315 putative CheW protein.
       0.629
Afer_0212
CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; SMART: CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: aba:Acid345_1524 CheA signal transduction histidine kinases.
       0.627
Afer_0216
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; KEGG: dau:Daud_0059 GntR family transcriptional regulator.
       0.561
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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