STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0223KEGG: saq:Sare_4003 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12- binding domain protein. (647 aa)    
Predicted Functional Partners:
Afer_1780
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: saq:Sare_3990 LAO/AO transport system ATPase.
  
 0.997
Afer_0104
TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pho:PH0272 hypothetical protein.
  
 0.960
Afer_1770
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: lic:LIC13009 acyl-CoA dehydrogenase.
 
 
 0.946
Afer_0222
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: fre:Franean1_1037 3-hydroxybutyryl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase.
     
 0.910
Afer_0105
TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: stp:Strop_3612 crotonyl-CoA reductase.
   
 0.864
Afer_1791
methylmalonyl-CoA mutase, large subunit; KEGG: ace:Acel_0674 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase.
 
 
0.861
Afer_0726
methylmalonyl-CoA mutase, large subunit; KEGG: rxy:Rxyl_1283 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase.
 
 
0.856
Afer_0318
PFAM: cobalamin B12-binding domain protein; KEGG: sgr:SGR_2730 putative isobutyryl-CoA mutase, chain B.
 
 
0.853
Afer_1777
Citrate (pro-3S)-lyase; PFAM: HpcH/HpaI aldolase; KEGG: sgr:SGR_1172 putative lyase; Belongs to the HpcH/HpaI aldolase family.
  
 0.841
Afer_1603
PFAM: MaoC domain protein dehydratase; KEGG: saq:Sare_0676 dehydratase.
 
  
 0.840
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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