Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0230PFAM: BioY protein; KEGG: saq:Sare_4638 BioY protein. (204 aa)    
Predicted Functional Partners:
Afer_0231
PFAM: carboxyl transferase; KEGG: rca:Rcas_4102 carboxyl transferase.
       0.778
Afer_0229
PFAM: protein of unknown function DUF6 transmembrane; KEGG: sma:SAV_7066 integral membrane protein.
 
     0.604
Afer_0731
TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; KEGG: rpb:RPB_3299 biotin--acetyl-CoA-carboxylase ligase.
 
   
 0.603
Afer_0232
PFAM: Amidase; KEGG: mxa:MXAN_6372 6-aminohexanoate-cyclic-dimer hydrolase; Belongs to the amidase family.
       0.437
Afer_0233
PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: mxa:MXAN_0543 peptidase, M20 (glutamate carboxypeptidase) family.
       0.427
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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