Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_0233PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: mxa:MXAN_0543 peptidase, M20 (glutamate carboxypeptidase) family. (469 aa)    
Predicted Functional Partners:
Afer_0232
PFAM: Amidase; KEGG: mxa:MXAN_6372 6-aminohexanoate-cyclic-dimer hydrolase; Belongs to the amidase family.
     
 0.755
Afer_0661
PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: tfu:Tfu_0495 dipeptidase.
  
   
 0.461
Afer_0231
PFAM: carboxyl transferase; KEGG: rca:Rcas_4102 carboxyl transferase.
  
    0.458
Afer_0230
PFAM: BioY protein; KEGG: saq:Sare_4638 BioY protein.
       0.427
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
 
 
 0.408
argG
KEGG: fra:Francci3_3169 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; ExsB family protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.403
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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