Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Afer_0237PFAM: Anion-transporting ATPase; KEGG: rha:RHA1_ro04317 arsenate (2+)-transporting ATPase. (353 aa)    
Predicted Functional Partners:
Afer_0238
PFAM: Anion-transporting ATPase; KEGG: ank:AnaeK_0988 chromosome partitioning-like ATPase.
 
 
   0.984
Afer_0236
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: bur:Bcep18194_B3050 two component transcriptional regulator.
       0.761
Afer_0349
KEGG: ade:Adeh_0929 chromosome partitioning-like ATPase.
 
 
  
0.759
Afer_0938
PFAM: cyclase/dehydrase; KEGG: fal:FRAAL0171 hypothetical protein.
 
    0.708
Afer_1697
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
    
   0.644
Afer_0235
PFAM: NUDIX hydrolase; KEGG: maq:Maqu_3801 beta-lactamase domain- containing protein.
 
     0.641
Afer_0234
Protein of unknown function DUF59; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.492
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
 
   0.468
Afer_1737
PFAM: ABC-1 domain protein; KEGG: fal:FRAAL6034 ABC transporter, ATP-binding protein.
  
     0.460
Afer_0896
PFAM: Tetratricopeptide TPR_2 repeat protein; Tetratricopeptide TPR_4; KEGG: stp:Strop_1906 tetratricopeptide TPR_4.
    
 0.420
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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