Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Afer_0244KEGG: kra:Krad_4317 hypothetical protein. (189 aa)    
Predicted Functional Partners:
Afer_0245
Conserved hypothetical protein; KEGG: bwe:BcerKBAB4_1354 peptidase M23B.
       0.773
Afer_0580
PFAM: conserved hypothetical protein; KEGG: fal:FRAAL0333 hypothetical protein.
 
   
 0.595
Afer_1742
TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation D domain protein; Two component regulator propeller; KEGG: ace:Acel_0423 SpoIID/LytB domain-containing protein.
  
     0.539
Afer_0183
PFAM: Transglycosylase domain protein; KEGG: fre:Franean1_0215 transglycosylase domain- containing protein.
  
     0.522
Afer_0757
KEGG: sgr:SGR_5851 hypothetical protein.
  
     0.480
Afer_0344
PFAM: ABC-2 type transporter; KEGG: dra:DR_A0008 hypothetical protein.
  
   
 0.468
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
    0.409
Afer_0712
TIGRFAM: HhH-GPD family protein; PFAM: HhH-GPD family protein; KEGG: sma:SAV_4172 hypothetical protein.
 
     0.402
Afer_0247
Hypothetical protein.
       0.401
Afer_0248
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.401
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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