STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0244KEGG: kra:Krad_4317 hypothetical protein. (189 aa)    
Predicted Functional Partners:
Afer_0245
Conserved hypothetical protein; KEGG: bwe:BcerKBAB4_1354 peptidase M23B.
       0.773
Afer_0580
PFAM: conserved hypothetical protein; KEGG: fal:FRAAL0333 hypothetical protein.
 
     0.580
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.
       0.562
Afer_1742
TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation D domain protein; Two component regulator propeller; KEGG: ace:Acel_0423 SpoIID/LytB domain-containing protein.
  
     0.539
pheT
KEGG: ade:Adeh_1971 phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
     
 0.533
Afer_0183
PFAM: Transglycosylase domain protein; KEGG: fre:Franean1_0215 transglycosylase domain- containing protein.
  
     0.522
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
       0.493
lipB
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the LipB family.
       0.487
Afer_0757
KEGG: sgr:SGR_5851 hypothetical protein.
  
     0.480
Afer_0344
PFAM: ABC-2 type transporter; KEGG: dra:DR_A0008 hypothetical protein.
  
   
 0.472
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.