STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0256PFAM: metallophosphoesterase; KEGG: pzu:PHZ_c0307 3',5'-cyclic-nucleotide phosphodiesterase. (292 aa)    
Predicted Functional Partners:
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.902
Afer_1956
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tth:TTC1149 putative adenylosuccinate lyase protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
  0.900
Afer_0694
PFAM: major facilitator superfamily MFS_1; KEGG: ace:Acel_1472 major facilitator transporter.
  
     0.658
Afer_1882
KEGG: ace:Acel_0470 hypothetical protein.
  
     0.565
Afer_1473
KEGG: sus:Acid_7587 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
  
     0.535
Afer_1772
PFAM: peptidase C60 sortase A and B; KEGG: kra:Krad_3106 peptidase C60 sortase A and B.
  
   
 0.524
Afer_0257
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; Male sterility domain; KEGG: sru:SRU_2037 short chain dehydrogenase/reductase family oxidoreductase.
  
    0.506
Afer_1789
PFAM: regulatory protein TetR; KEGG: sgr:SGR_6910 TetR family transcriptional regulator.
  
     0.505
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
       0.500
Afer_1637
PFAM: protein of unknown function DUF1707; KEGG: sco:SCO2893 hypothetical protein.
  
     0.499
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.