Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0258KEGG: cef:CE1107 hypothetical protein. (240 aa)    
Predicted Functional Partners:
Afer_0259
KEGG: kra:Krad_1834 hypothetical protein.
 
    0.961
Afer_0260
PFAM: Phosphoglycerate mutase; KEGG: cgt:cgR_1141 hypothetical protein.
 
     0.932
Afer_1396
PFAM: helicase domain protein; SNF2-related protein; SMART: helicase domain protein; DEAD-like helicases; KEGG: cte:CT0906 DNA-dependent ATPase, SNF2 family protein.
   
 0.853
Afer_1609
PFAM: LmbE family protein; KEGG: sen:SACE_0909 N- acetylglucosaminylphosphatidylinositol deacetylase.
  
     0.765
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
    
   0.728
Afer_0264
PFAM: LmbE family protein; KEGG: ace:Acel_0374 LmbE family protein.
 
     0.709
mshD
Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
     0.678
Afer_0167
PFAM: phosphoribulokinase/uridine kinase; KEGG: gvi:glr4424 phosphoribulokinase.
    
  0.577
Afer_0670
KEGG: tfu:Tfu_0325 hypothetical protein.
  
     0.575
Afer_0590
PFAM: protein of unknown function DUF121; KEGG: nfa:nfa42070 hypothetical protein.
  
     0.574
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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