STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0270PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: hau:Haur_0337 ABC transporter related. (626 aa)    
Predicted Functional Partners:
Afer_0523
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sma:SAV_4258 ABC transporter ATP-binding protein.
 
   
0.904
Afer_1059
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: nca:Noca_2866 ABC transporter related.
   
0.879
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
 
     
0.877
Afer_0728
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: mxa:MXAN_2588 molybdopterin biosynthesis protein MoeB.
  
 
 0.616
Afer_0271
TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase; KEGG: fal:FRAAL4424 putative reductase.
  
    0.561
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.549
Afer_0286
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicases; helicase domain protein; KEGG: pac:PPA1787 ATP-dependent RNA helicase.
 
 
 
 0.534
Afer_0024
PFAM: histone deacetylase superfamily; KEGG: sul:SYO3AOP1_1212 histone deacetylase superfamily.
   
 0.532
arc
AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
 
  0.512
Afer_0191
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tfu:Tfu_1989 ABC-type multidrug transport system ATPase componen.
 
0.487
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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