Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_0272PFAM: NAD-glutamate dehydrogenase; KEGG: ace:Acel_1749 glutamate dehydrogenase (NAD). (1518 aa)    
Predicted Functional Partners:
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
     
 0.939
Afer_1378
PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: ote:Oter_0715 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.938
Afer_0242
PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sat:SYN_01628 glutamine synthetase.
     
 0.935
Afer_0243
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: fre:Franean1_1770 glutamine synthetase, type I.
     
 0.935
Afer_1967
PFAM: glutamine synthetase catalytic region; KEGG: fra:Francci3_0315 L-glutamine synthetase.
     
 0.911
Afer_1450
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dsy:DSY3404 hypothetical protein.
     
 0.908
Afer_1987
TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mkm:Mkms_5153 glutamate synthase subunit beta.
     
 0.908
Afer_1640
TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; KEGG: bca:BCE_2691 glutamate decarboxylase; Belongs to the group II decarboxylase family.
     
 0.907
Afer_1531
PFAM: aminotransferase class I and II; KEGG: rsa:RSal33209_0984 aspartate aminotransferase.
     
 0.906
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
     
  0.900
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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