Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0273TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: nca:Noca_3382 agmatinase; Belongs to the arginase family. (317 aa)    
Predicted Functional Partners:
Afer_1378
PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: ote:Oter_0715 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.937
Afer_0232
PFAM: Amidase; KEGG: mxa:MXAN_6372 6-aminohexanoate-cyclic-dimer hydrolase; Belongs to the amidase family.
     
  0.900
Afer_1194
PFAM: Amidase; KEGG: bmj:BMULJ_03430 amidase; Belongs to the amidase family.
     
  0.900
Afer_1458
PFAM: Amidase; KEGG: sen:SACE_2834 secreted amidase.
     
  0.900
Afer_1642
Hypothetical protein; KEGG: rha:RHA1_ro04406 amidase.
     
  0.900
Afer_0272
PFAM: NAD-glutamate dehydrogenase; KEGG: ace:Acel_1749 glutamate dehydrogenase (NAD).
    
 0.893
Afer_0329
PFAM: Formiminotransferase domain protein; KEGG: sat:SYN_00461 glutamate formiminotransferase.
  
    0.878
Afer_0700
PFAM: aminotransferase class-III; KEGG: rca:Rcas_3219 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.826
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
    
 0.824
Afer_0242
PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sat:SYN_01628 glutamine synthetase.
     
 0.813
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.