STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0274Transcriptional regulator, XRE family; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: art:Arth_0847 transcriptional regulator, XRE family with cupin sensor. (205 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.806
Afer_1172
Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; Rhodanese domain protein; KEGG: rha:RHA1_ro11220 ArsR family transcriptional regulator.
  
  
 0.765
Afer_1409
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sgr:SGR_1276 GntR family transcriptional regulator.
 
  
 0.699
Afer_0652
TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; KEGG: fal:FRAAL5732 competence-inducible (CinA- like) protein; Belongs to the CinA family.
  
  
 0.697
Afer_1614
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: dsy:DSY4747 hypothetical protein.
 
  
 0.694
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
  
  
 0.664
Afer_0273
TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: nca:Noca_3382 agmatinase; Belongs to the arginase family.
 
   
 0.661
Afer_0275
Hypothetical protein.
       0.658
Afer_0276
PFAM: protein of unknown function DUF1614; KEGG: bbt:BBta_0662 hypothetical protein.
       0.658
Afer_1888
KEGG: art:Arth_4271 hypothetical protein.
  
    0.654
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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