Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0274Transcriptional regulator, XRE family; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: art:Arth_0847 transcriptional regulator, XRE family with cupin sensor. (205 aa)    
Predicted Functional Partners:
Afer_1172
Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; Rhodanese domain protein; KEGG: rha:RHA1_ro11220 ArsR family transcriptional regulator.
  
  
 0.780
Afer_1409
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sgr:SGR_1276 GntR family transcriptional regulator.
 
  
 0.718
Afer_1614
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: dsy:DSY4747 hypothetical protein.
 
  
 0.713
Afer_0273
TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: nca:Noca_3382 agmatinase; Belongs to the arginase family.
 
   
 0.685
Afer_1888
KEGG: art:Arth_4271 hypothetical protein.
  
    0.680
Afer_0063
Putative transcriptional regulator, GntR family.
  
  
 0.670
Afer_0608
PFAM: peptidase C26; glutamine amidotransferase class-I; KEGG: mta:Moth_2164 peptidase C26.
 
  
 0.660
Afer_0275
Hypothetical protein.
       0.658
Afer_0276
PFAM: protein of unknown function DUF1614; KEGG: bbt:BBta_0662 hypothetical protein.
       0.658
Afer_2004
PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: msm:MSMEG_6700 regulatory protein.
 
  
 0.649
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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