STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0283KEGG: mab:MAB_2457c hypothetical protein. (170 aa)    
Predicted Functional Partners:
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
       0.562
Afer_0652
TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; KEGG: fal:FRAAL5732 competence-inducible (CinA- like) protein; Belongs to the CinA family.
  
    0.561
Afer_0183
PFAM: Transglycosylase domain protein; KEGG: fre:Franean1_0215 transglycosylase domain- containing protein.
  
     0.560
Afer_0454
KEGG: tfu:Tfu_2983 hypothetical protein.
  
     0.499
Afer_1064
PFAM: protein of unknown function DUF1212; KEGG: rha:RHA1_ro04718 amino acid export carrier protein.
  
     0.457
Afer_0258
KEGG: cef:CE1107 hypothetical protein.
  
     0.437
Afer_0282
Hypothetical protein; KEGG: rha:RHA1_ro01864 mycothiol-dependent maleylpyruvate isomerase.
       0.437
vapC
PilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
     0.426
Afer_0794
KEGG: mmi:MMAR_0699 hypothetical protein.
  
     0.419
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.