STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0294Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: nfa:nfa3250 putative ferric uptake regulator; Belongs to the Fur family. (170 aa)    
Predicted Functional Partners:
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
 0.901
Afer_0199
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: fra:Francci3_2661 ferric uptake regulator family protein; Belongs to the Fur family.
  
     0.763
Afer_1453
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: cts:Ctha_1302 ferric uptake regulator, Fur family; Belongs to the Fur family.
  
   
 0.755
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.720
Afer_0859
Peroxidase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: xau:Xaut_2363 peroxidase.
  
  
 0.601
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
     
 0.587
Afer_0346
KEGG: saq:Sare_3145 transcriptional regulator, TrmB.
  
    0.586
Afer_0079
PFAM: CoA-binding domain protein; KEGG: spe:Spro_1762 CoA-binding domain-containing protein.
  
    0.513
Afer_0293
PFAM: pyridine nucleotide-disulphide oxidoreductase dimerization region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: min:Minf_1201 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme.
  
    0.492
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.483
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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