Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Afer_0296PFAM: protein of unknown function DUF74; KEGG: afe:Lferr_1683 hypothetical protein. (290 aa)    
Predicted Functional Partners:
Afer_0999
Hypothetical protein; KEGG: nca:Noca_3830 ferric reductase domain- containing protein.
  
     0.719
Afer_1071
PFAM: Peptidase S53 propeptide; KEGG: bph:Bphy_5054 peptidase S53 propeptide.
  
     0.707
Afer_0081
PFAM: Peptidase S53 propeptide; KEGG: cac:CAC0625 periplasmic aspartyl protease.
  
     0.668
Afer_0196
PFAM: Peptidase S53 propeptide; KEGG: cac:CAC0625 periplasmic aspartyl protease.
  
     0.665
Afer_0463
Hypothetical protein; KEGG: ace:Acel_1450 RND family efflux transporter MFP subunit.
  
     0.596
Afer_0476
KEGG: ace:Acel_0596 natural resistance-associated macrophage protein.
  
     0.595
Afer_0781
KEGG: acr:Acry_2205 extracellular ligand-binding receptor.
  
     0.571
Afer_1934
KEGG: bvi:Bcep1808_7294 tungstate/molybdate binding protein.
  
     0.561
Afer_0297
PFAM: major facilitator superfamily MFS_1; protein of unknown function DUF894 DitE; KEGG: sma:SAV_3894 integral membrane efflux protein.
       0.548
Afer_1523
PFAM: Cytochrome b/b6 domain; KEGG: ace:Acel_1781 hypothetical protein.
  
     0.535
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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