STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0325PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: acr:Acry_3608 general substrate transporter. (477 aa)    
Predicted Functional Partners:
Afer_1035
PFAM: amino acid permease-associated region; KEGG: acr:Acry_0648 amino acid permease-associated region.
  
     0.583
Afer_1934
KEGG: bvi:Bcep1808_7294 tungstate/molybdate binding protein.
  
     0.531
Afer_0948
PFAM: amino acid permease-associated region; KEGG: tac:Ta0427 L-asparagine permease related protein.
  
     0.528
Afer_1213
PFAM: amino acid permease-associated region; KEGG: tac:Ta0427 L-asparagine permease related protein.
  
     0.526
Afer_0324
PFAM: methylenetetrahydrofolate reductase; KEGG: ttj:TTHA0327 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
    0.495
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.494
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
       0.484
purH
IMP cyclohydrolase; KEGG: kra:Krad_3995 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; SMART: AICARFT/IMPCHase bienzyme formylation region.
       0.484
Afer_1969
PFAM: amino acid permease-associated region; KEGG: acr:Acry_0648 amino acid permease-associated region.
  
     0.479
Afer_1181
PFAM: amino acid permease-associated region; KEGG: afe:Lferr_0867 amino acid permease-associated region.
  
     0.441
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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