Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
whiB-3Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (97 aa)    
Predicted Functional Partners:
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
   0.884
Afer_0329
PFAM: Formiminotransferase domain protein; KEGG: sat:SYN_00461 glutamate formiminotransferase.
       0.812
Afer_1496
KEGG: kra:Krad_1406 hypothetical protein.
  
     0.774
Afer_0248
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
   0.759
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.759
Afer_0352
PFAM: histidine kinase dimerization/phosphoacceptor; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: ace:Acel_0559 signal transduction histidine kinase.
  
     0.720
Afer_1829
KEGG: sen:SACE_5730 ATP-dependent DNA helicase.
  
     0.697
Afer_0918
PFAM: DEAD/DEAH box helicase domain protein; DSH domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: ace:Acel_1206 DSH domain-containing protein.
  
     0.604
Afer_0194
PFAM: ATP-dependent Clp protease adaptor protein ClpS; KEGG: rha:RHA1_ro01441 ATP-dependent Clp protease adaptor protein ClpS; Belongs to the ClpS family.
  
     0.592
Afer_0852
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
     0.588
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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