STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0333PFAM: cytochrome c-type biogenesis protein CcmB; ABC-2 type transporter; KEGG: nca:Noca_1953 cytochrome c-type biogenesis protein CcmB. (221 aa)    
Predicted Functional Partners:
Afer_0334
PFAM: cytochrome c assembly protein; KEGG: nca:Noca_1955 cytochrome c assembly protein.
 
 0.999
Afer_0332
Heme exporter protein CcmA; KEGG: nca:Noca_1952 ABC transporter related; TIGRFAM: heme exporter protein CcmA; PFAM: ABC transporter related; SMART: AAA ATPase.
  
 0.997
Afer_0336
CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
 
 
 0.958
Afer_0337
PFAM: cytochrome c assembly protein; KEGG: nca:Noca_1958 cytochrome c assembly protein.
 
  
 0.922
Afer_0339
Cytochrome C biogenesis protein; Possible subunit of a heme lyase.
 
   
 0.851
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
       0.807
Afer_0338
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: mgm:Mmc1_3503 periplasmic protein thiol-- disulphide oxidoreductase DsbE.
 
  
 0.721
Afer_0330
PFAM: regulatory protein TetR; KEGG: rsa:RSal33209_1214 TetR family transcriptional regulator.
 
     0.606
Afer_0251
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sus:Acid_3181 uroporphyrinogen-III C- methyltransferase / uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family.
       0.550
Afer_1710
PFAM: Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thioredoxin domain; KEGG: ttj:TTHA1728 hypothetical protein.
 
  
 0.420
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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