Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0338PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: mgm:Mmc1_3503 periplasmic protein thiol-- disulphide oxidoreductase DsbE. (180 aa)    
Predicted Functional Partners:
Afer_0337
PFAM: cytochrome c assembly protein; KEGG: nca:Noca_1958 cytochrome c assembly protein.
 
  
 0.969
Afer_0339
Cytochrome C biogenesis protein; Possible subunit of a heme lyase.
 
  
 0.917
Afer_0334
PFAM: cytochrome c assembly protein; KEGG: nca:Noca_1955 cytochrome c assembly protein.
 
  
 0.907
Afer_0336
CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
 
  
 0.903
Afer_0859
Peroxidase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: xau:Xaut_2363 peroxidase.
  
 0.885
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.821
Afer_0030
KEGG: fra:Francci3_4536 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase.
  
 
 0.776
Afer_1690
Hypothetical protein; KEGG: lch:Lcho_0048 electron transport protein SCO1/SenC.
  
 
 0.744
Afer_0333
PFAM: cytochrome c-type biogenesis protein CcmB; ABC-2 type transporter; KEGG: nca:Noca_1953 cytochrome c-type biogenesis protein CcmB.
 
  
 0.740
Afer_1129
PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: mgm:Mmc1_0245 cytochrome c biogenesis protein, transmembrane region.
 
  
 0.692
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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