Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_0340PFAM: oxidoreductase molybdopterin binding; KEGG: rca:Rcas_2793 oxidoreductase molybdopterin binding. (205 aa)    
Predicted Functional Partners:
Afer_1827
PFAM: cytochrome c class I; KEGG: fre:Franean1_1810 cytochrome c class I.
   
 
 0.786
Afer_0338
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: mgm:Mmc1_3503 periplasmic protein thiol-- disulphide oxidoreductase DsbE.
   
 
 0.561
Afer_0337
PFAM: cytochrome c assembly protein; KEGG: nca:Noca_1958 cytochrome c assembly protein.
     
 0.518
Afer_0339
Cytochrome C biogenesis protein; Possible subunit of a heme lyase.
       0.516
Afer_0336
CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
       0.511
Afer_0341
PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: afe:Lferr_1484 major facilitator superfamily MFS_1.
       0.483
Afer_1020
PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; KEGG: cau:Caur_3201 nitrate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
   
 0.452
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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