STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0342Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; KEGG: sco:SCO4072 LuxR family two component system response regulator. (196 aa)    
Predicted Functional Partners:
Afer_0343
Putative signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: sco:SCO2307 two-component sensor kinase.
 
 0.996
Afer_0181
PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase dimerization and phosphoacceptor region; SMART: GAF domain protein; ATP-binding region ATPase domain protein; KEGG: mkm:Mkms_1071 GAF sensor signal transduction histidine kinase.
 
 
 0.859
Afer_1982
Putative signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: kra:Krad_1351 integral membrane sensor signal transduction histidine kinase.
 
 
 0.851
Afer_0344
PFAM: ABC-2 type transporter; KEGG: dra:DR_A0008 hypothetical protein.
 
   
 0.821
Afer_0345
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sco:SCO2305 ABC transporter ATP-binding subunit.
  
  
 0.777
Afer_1981
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Bacterio-opsin activator HTH domain protein; SMART: regulatory protein LuxR; response regulator receiver; KEGG: cms:CMS_0994 putative two-component system response regulator.
  
     0.773
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.