Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0346KEGG: saq:Sare_3145 transcriptional regulator, TrmB. (245 aa)    
Predicted Functional Partners:
Afer_1562
PFAM: protein of unknown function DUF501; KEGG: rxy:Rxyl_0915 hypothetical protein.
  
     0.682
Afer_0859
Peroxidase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: xau:Xaut_2363 peroxidase.
  
    0.631
Afer_0348
KEGG: lxx:Lxx09210 hypothetical protein.
 
     0.623
Afer_0199
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: fra:Francci3_2661 ferric uptake regulator family protein; Belongs to the Fur family.
  
    0.596
Afer_0294
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: nfa:nfa3250 putative ferric uptake regulator; Belongs to the Fur family.
  
    0.596
Afer_1453
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: cts:Ctha_1302 ferric uptake regulator, Fur family; Belongs to the Fur family.
  
    0.596
Afer_0347
Protein of unknown function DUF59; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.573
Afer_0039
KEGG: ace:Acel_2136 hypothetical protein.
  
     0.571
Afer_1254
PFAM: biotin/lipoate A/B protein ligase; KEGG: cau:Caur_3882 biotin/lipoate A/B protein ligase.
  
     0.568
Afer_1409
Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sgr:SGR_1276 GntR family transcriptional regulator.
   
  
 0.555
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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