Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0349KEGG: ade:Adeh_0929 chromosome partitioning-like ATPase. (306 aa)    
Predicted Functional Partners:
Afer_0350
ATPase involved in chromosome partitioning; KEGG: fre:Franean1_0335 anion-transporting ATPase.
 
 
   0.984
Afer_0348
KEGG: lxx:Lxx09210 hypothetical protein.
       0.804
Afer_0352
PFAM: histidine kinase dimerization/phosphoacceptor; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: ace:Acel_0559 signal transduction histidine kinase.
       0.801
Afer_0351
PFAM: PHP domain protein; KEGG: tpd:Teth39_0146 HisJ family histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.
       0.767
Afer_0237
PFAM: Anion-transporting ATPase; KEGG: rha:RHA1_ro04317 arsenate (2+)-transporting ATPase.
 
 
  
0.759
Afer_1697
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
    
   0.644
Afer_0347
Protein of unknown function DUF59; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.633
Afer_0353
PFAM: Electron transfer flavoprotein alpha/beta- subunit; KEGG: sen:SACE_6197 electron transfer flavoprotein, beta subunit.
       0.552
Afer_0354
PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; KEGG: ace:Acel_0685 electron transfer flavoprotein, alpha subunit.
  
    0.546
Afer_0938
PFAM: cyclase/dehydrase; KEGG: fal:FRAAL0171 hypothetical protein.
 
    0.518
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.