Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0378PFAM: protein of unknown function DUF470; protein of unknown function DUF472; protein of unknown function DUF471; KEGG: sma:SAV_4673 hypothetical protein. (938 aa)    
Predicted Functional Partners:
lysS
TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); tRNA synthetase class II (G H P and S); nucleic acid binding OB- fold tRNA/helicase-type; KEGG: cya:CYA_0333 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 
 0.990
Afer_0379
PFAM: protein of unknown function DUF520; KEGG: saq:Sare_0477 nucleotide-binding protein; Belongs to the UPF0234 family.
       0.776
Afer_0377
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: stp:Strop_0725 short-chain dehydrogenase/reductase SDR.
       0.773
Afer_0380
KEGG: sen:SACE_2172 hypothetical protein.
 
     0.664
Afer_0606
KEGG: fra:Francci3_2206 hypothetical protein.
  
     0.634
Afer_1922
PFAM: nucleic acid binding OB-fold tRNA/helicase- type; amino acid permease-associated region; KEGG: ace:Acel_1194 nucleic acid binding, OB-fold, tRNA/helicase-type.
  
     0.546
Afer_0381
PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; KEGG: met:M446_4878 HhH-GPD family protein.
       0.475
Afer_1141
PFAM: extracellular solute-binding protein family 5; KEGG: saq:Sare_2145 extracellular solute-binding protein.
  
     0.463
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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