Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0380KEGG: sen:SACE_2172 hypothetical protein. (522 aa)    
Predicted Functional Partners:
Afer_0381
PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; KEGG: met:M446_4878 HhH-GPD family protein.
       0.777
Afer_0682
KEGG: fra:Francci3_1402 hypothetical protein.
  
     0.723
Afer_0378
PFAM: protein of unknown function DUF470; protein of unknown function DUF472; protein of unknown function DUF471; KEGG: sma:SAV_4673 hypothetical protein.
 
     0.664
Afer_1733
PFAM: alpha/beta hydrolase fold; KEGG: fre:Franean1_2175 alpha/beta hydrolase fold.
  
 
   0.648
Afer_0039
KEGG: ace:Acel_2136 hypothetical protein.
  
     0.594
Afer_1882
KEGG: ace:Acel_0470 hypothetical protein.
  
     0.572
Afer_0809
KEGG: rha:RHA1_ro01772 hypothetical protein.
  
     0.545
Afer_0377
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: stp:Strop_0725 short-chain dehydrogenase/reductase SDR.
   
   0.531
secE
Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
  
     0.526
Afer_1990
PFAM: Colicin V production protein; peptidase S1 and S6 chymotrypsin/Hap; KEGG: ace:Acel_1988 peptidase S1 and S6, chymotrypsin/Hap.
  
   0.487
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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