STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0381PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; KEGG: met:M446_4878 HhH-GPD family protein. (250 aa)    
Predicted Functional Partners:
Afer_1727
TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: ace:Acel_1469 exodeoxyribonuclease III.
  
 0.876
Afer_0380
KEGG: sen:SACE_2172 hypothetical protein.
       0.778
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.702
Afer_0377
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: stp:Strop_0725 short-chain dehydrogenase/reductase SDR.
  
    0.483
Afer_0378
PFAM: protein of unknown function DUF470; protein of unknown function DUF472; protein of unknown function DUF471; KEGG: sma:SAV_4673 hypothetical protein.
       0.475
Afer_0379
PFAM: protein of unknown function DUF520; KEGG: saq:Sare_0477 nucleotide-binding protein; Belongs to the UPF0234 family.
       0.475
Afer_1612
KEGG: fal:FRAAL2179 putative DNA-directed DNA polymerase.
  
 
 0.401
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.