Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Afer_0454KEGG: tfu:Tfu_2983 hypothetical protein. (258 aa)    
Predicted Functional Partners:
crcB
Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.636
Afer_0456
PFAM: protein of unknown function DUF190; KEGG: nca:Noca_2956 hypothetical protein.
       0.636
crcB-2
Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.636
Afer_0458
Hypothetical protein; KEGG: cyt:cce_0886 phosphate ABC transporter, periplasmic phosphate-binding protein.
       0.636
Afer_0459
TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase; KEGG: rxy:Rxyl_0815 inositol-5-monophosphate dehydrogenase.
  
 
 0.592
Afer_0235
PFAM: NUDIX hydrolase; KEGG: maq:Maqu_3801 beta-lactamase domain- containing protein.
  
     0.538
Afer_1882
KEGG: ace:Acel_0470 hypothetical protein.
  
     0.504
Afer_0283
KEGG: mab:MAB_2457c hypothetical protein.
  
     0.499
Afer_1784
PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; KEGG: mab:MAB_3296 hypothetical protein.
 
     0.498
Afer_1563
PFAM: carbon monoxide dehydrogenase subunit G; Activator of Hsp90 ATPase 1 family protein; KEGG: fre:Franean1_3210 carbon monoxide dehydrogenase subunit G.
  
     0.496
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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