STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0456PFAM: protein of unknown function DUF190; KEGG: nca:Noca_2956 hypothetical protein. (112 aa)    
Predicted Functional Partners:
crcB
Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
 
   
 0.904
crcB-2
Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
 
   
 0.850
Afer_0458
Hypothetical protein; KEGG: cyt:cce_0886 phosphate ABC transporter, periplasmic phosphate-binding protein.
       0.773
Afer_0454
KEGG: tfu:Tfu_2983 hypothetical protein.
       0.636
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
       0.572
Afer_0459
TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase; KEGG: rxy:Rxyl_0815 inositol-5-monophosphate dehydrogenase.
       0.548
Afer_0461
PFAM: UvrD/REP helicase; KEGG: tfu:Tfu_2580 ATP-dependent DNA helicase PcrA.
       0.541
Afer_0186
PFAM: GCN5-related N-acetyltransferase; KEGG: cvi:CV_3058 hypothetical protein.
  
     0.527
Afer_1637
PFAM: protein of unknown function DUF1707; KEGG: sco:SCO2893 hypothetical protein.
  
     0.466
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.