Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_0464PFAM: glycosyl transferase family 2; KEGG: mkm:Mkms_4650 glycosyl transferase, family 2. (631 aa)    
Predicted Functional Partners:
Afer_0463
Hypothetical protein; KEGG: ace:Acel_1450 RND family efflux transporter MFP subunit.
 
  
 0.833
Afer_0896
PFAM: Tetratricopeptide TPR_2 repeat protein; Tetratricopeptide TPR_4; KEGG: stp:Strop_1906 tetratricopeptide TPR_4.
  
 
 0.779
Afer_0465
Hypothetical protein.
       0.773
Afer_0462
UDP-sulfoquinovose synthase; PFAM: NAD-dependent epimerase/dehydratase; KEGG: rrs:RoseRS_0861 NAD-dependent epimerase/dehydratase.
 
 
 0.719
Afer_1949
PFAM: General secretory system II protein E domain protein; glycosyl transferase family 2; KEGG: ttj:TTHA0743 glycosyltransferase related protein.
  
     0.687
Afer_0466
Hypothetical protein.
       0.655
Afer_0467
Hypothetical protein.
       0.498
Afer_0459
TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase; KEGG: rxy:Rxyl_0815 inositol-5-monophosphate dehydrogenase.
     
 0.465
Afer_0129
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: afe:Lferr_1378 cobyrinic acid ac-diamide synthase.
  
 
 0.463
Afer_2031
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: cth:Cthe_2377 chromosome segregation ATPase.
  
 
 0.463
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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