STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0475PFAM: MgtE intracellular region; CBS domain containing protein; SMART: CBS domain containing protein; KEGG: mav:MAV_2122 MgtE intracellular domain family protein. (413 aa)    
Predicted Functional Partners:
Afer_0474
PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: dge:Dgeo_2010 PHP-like protein.
       0.673
Afer_0472
PFAM: peptidase U62 modulator of DNA gyrase; KEGG: hmo:HM1_0268 modulator of DNA gyrase, putative.
       0.664
Afer_0473
PFAM: peptidase U62 modulator of DNA gyrase; KEGG: pth:PTH_1159 Zn-dependent protease.
       0.664
Afer_0476
KEGG: ace:Acel_0596 natural resistance-associated macrophage protein.
 
  
 0.622
Afer_0308
KEGG: mav:MAV_4571 metal ion transporter, nramp family protein.
 
  
 0.523
Afer_0469
PFAM: Squalene/phytoene synthase; KEGG: saq:Sare_4931 squalene/phytoene synthase.
       0.464
Afer_0470
TIGRFAM: phytoene desaturase; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: nfa:nfa43990 putative phytoene desaturase.
       0.464
Afer_0471
PFAM: Polyprenyl synthetase; KEGG: saq:Sare_3478 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
       0.464
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.451
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.