STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0493PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: ank:AnaeK_2441 peptidase M1 membrane alanine aminopeptidase. (852 aa)    
Predicted Functional Partners:
Afer_0492
KEGG: sgr:SGR_5196 hypothetical protein.
     
 0.792
Afer_0494
PFAM: PfkB domain protein; KEGG: rru:Rru_A0149 PfkB; Belongs to the carbohydrate kinase PfkB family.
 
 
   0.667
Afer_0811
Endothelin-converting enzyme 1; PFAM: peptidase M13; peptidase M13 neprilysin; KEGG: lxx:Lxx01010 metallopeptidase.
 
   
 0.621
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
   
 
 0.527
Afer_1226
Small GTP-binding protein; KEGG: rha:RHA1_ro05886 elongation factor EF2; TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain IV; elongation factor G domain protein; Miro domain protein; GTP-binding protein HSR1-related; protein synthesis factor GTP- binding; SMART: AAA ATPase.
   
 
 0.524
Afer_1947
Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; amino acid-binding ACT domain protein; malic protein domain protein; UBA/THIF- type NAD/FAD binding protein; KEGG: rxy:Rxyl_1110 malate dehydrogenase (oxaloacetate decarboxylating).
  
 
 0.474
Afer_0286
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicases; helicase domain protein; KEGG: pac:PPA1787 ATP-dependent RNA helicase.
  
 
 0.441
Afer_1547
TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; KEGG: kra:Krad_1335 acetolactate synthase 1 catalytic subunit.
 
  
 
 0.426
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 
 0.421
Afer_0298
PFAM: NLP/P60 protein; KEGG: sgr:SGR_2734 NLP/P60 family secreted protein.
  
  
 0.413
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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