Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Afer_0495PFAM: glycoside hydrolase 15-related; KEGG: ote:Oter_3331 glycoside hydrolase 15-related. (850 aa)    
Predicted Functional Partners:
Afer_1849
PFAM: glycosyl transferase family 20; KEGG: sco:SCO4290 trehalose-phosphate synthase.
 
   
 0.881
Afer_1850
TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; trehalose-phosphatase; PFAM: trehalose-phosphatase; KEGG: saq:Sare_0810 HAD family hydrolase.
 
   
 0.778
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
       0.656
Afer_0497
PFAM: ROK family protein; KEGG: gka:GK2442 glucokinase.
  
    0.630
Afer_0838
PFAM: MscS Mechanosensitive ion channel; KEGG: bcm:Bcenmc03_1911 MscS mechanosensitive ion channel.
 
    0.627
Afer_1778
KEGG: fal:FRAAL5900 trehalose synthase (maltose alpha-D-glucosyltransferase); TIGRFAM: trehalose synthase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain.
 
   
 0.580
Afer_0498
PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: pto:PTO1267 transporter.
       0.554
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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