STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0497PFAM: ROK family protein; KEGG: gka:GK2442 glucokinase. (289 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.955
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: nfa:nfa49980 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.939
Afer_1766
PFAM: sugar isomerase (SIS); KEGG: dau:Daud_0299 bifunctional phosphoglucose/phosphomannose isomerase.
 
 
 0.928
Afer_1522
PFAM: Aldose 1-epimerase; KEGG: saq:Sare_0514 aldose 1-epimerase.
    
 0.919
Afer_0166
TIGRFAM: transketolase; fructose-1,6- bisphosphatase, class II; PFAM: GlpX family protein; Transketolase domain protein; Transketolase central region; KEGG: ttj:TTHA0108 transketolase; Belongs to the transketolase family.
  
 
 0.903
Afer_0037
PFAM: Myo-inositol-1-phosphate synthase; Myo- inositol-1-phosphate synthase GAPDH domain protein; KEGG: saq:Sare_5081 myo-inositol-1-phosphate synthase.
     
  0.900
zwf-2
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.871
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 
 0.844
Afer_0895
PFAM: deoxyribose-phosphate aldolase/phospho-2- dehydro-3-deoxyheptonate aldolase; KEGG: cts:Ctha_2362 fructose-bisphosphate aldolase.
    
 0.824
Afer_0177
PFAM: fructose-bisphosphate aldolase class-I; KEGG: ter:Tery_1687 fructose-bisphosphate aldolase.
     
 0.801
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.