Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0503PFAM: Extracellular ligand-binding receptor; KEGG: hwa:HQ3303A ABC-type branched-chain amino acid transport systems, substrate-binding protein. (429 aa)    
Predicted Functional Partners:
Afer_0506
PFAM: inner-membrane translocator; KEGG: cya:CYA_2478 hydrophobic amino acid ABC transporter permease; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.984
Afer_0507
PFAM: inner-membrane translocator; KEGG: csa:Csal_1420 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.978
Afer_0505
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: hwa:HQ2964A ABC-type branched-chain amino acid transport systems, ATP-binding protein I.
 
  
 0.970
Afer_0504
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cya:CYA_2623 hydrophobic amino acid ABC transporter ATP-binding protein.
 
  
 0.951
Afer_0779
PFAM: inner-membrane translocator; KEGG: acr:Acry_2203 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.925
Afer_0780
PFAM: inner-membrane translocator; KEGG: acr:Acry_2204 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.894
Afer_1081
PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver; KEGG: fre:Franean1_2035 response regulator receiver/ANTAR domain-containing protein.
  
 
 0.796
Afer_0778
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: acr:Acry_2202 ABC transporter related.
 
  
 0.747
Afer_0777
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: acr:Acry_2201 ABC transporter related.
 
  
 0.746
Afer_0665
PFAM: NMT1/THI5 like domain protein; KEGG: rpc:RPC_0844 ABC transporter substrate- binding protein.
  
  
 0.555
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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