Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Afer_0530PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aau:AAur_1330 tetrapyrrole methylase family protein. (286 aa)    
Predicted Functional Partners:
Afer_0532
TIGRFAM: GTP-binding protein YchF; PFAM: Protein of unknown function DUF933; GTP- binding protein HSR1-related; KEGG: kra:Krad_1124 translation-associated GTPase.
       0.787
Afer_0531
Hypothetical protein.
       0.773
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.759
Afer_0527
PFAM: ribosomal RNA adenine methylase transferase; SMART: ribosomal RNA adenine methylase transferase; KEGG: gtn:GTNG_0035 dimethyladenosine transferase.
     
 0.741
Afer_0528
TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; amidohydrolase 2; KEGG: scl:sce3778 TatD family deoxyribonuclease.
  
    0.735
rpsZ
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
   
 
 0.725
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
 
 0.724
ispE
GHMP kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
       0.721
rpsP
TIGRFAM: ribosomal protein S16; PFAM: ribosomal protein S16; KEGG: nth:Nther_1369 SSU ribosomal protein S16P; Belongs to the bacterial ribosomal protein bS16 family.
   
 
 0.697
rpsR
Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
 
 
 
 0.687
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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