Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_0567Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (416 aa)    
Predicted Functional Partners:
Afer_0566
TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; KEGG: rxy:Rxyl_0171 FeS assembly ATPase SufC.
  
 0.996
Afer_0568
TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: tth:TTC1374 IscU protein.
 
 
 0.996
Afer_0543
TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein; KEGG: rxy:Rxyl_0170 iron-regulated ABC transporter membrane component SufB.
 
 0.992
Afer_0563
KEGG: rce:RC1_0492 FeS assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase.
  
 0.965
Afer_0561
PFAM: SufBD protein; KEGG: rxy:Rxyl_0168 iron-regulated ABC transporter permease protein SufD.
 
 
 0.945
Afer_0030
KEGG: fra:Francci3_4536 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase.
 
 
  0.917
Afer_1495
PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: kra:Krad_1362 Cys/Met metabolism pyridoxal- phosphate-dependent protein.
     
 0.906
Afer_0728
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: mxa:MXAN_2588 molybdopterin biosynthesis protein MoeB.
  
 
 0.677
Afer_0565
KEGG: mjl:Mjls_0441 ferredoxin (3Fe-4S).
       0.548
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
  
  
 0.522
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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