Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0571PFAM: ATPase; KEGG: sen:SACE_7308 hypothetical protein. (461 aa)    
Predicted Functional Partners:
Afer_0572
KEGG: rha:RHA1_ro03229 glycerate kinase; TIGRFAM: glycerate kinase; PFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family.
       0.507
Afer_0812
PFAM: homogentisate 12-dioxygenase; KEGG: stp:Strop_4258 homogentisate 1,2-dioxygenase.
  
     0.464
Afer_1772
PFAM: peptidase C60 sortase A and B; KEGG: kra:Krad_3106 peptidase C60 sortase A and B.
  
     0.431
Afer_0344
PFAM: ABC-2 type transporter; KEGG: dra:DR_A0008 hypothetical protein.
  
     0.424
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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