Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_0578TIGRFAM: GTP-binding protein TypA; small GTP- binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: fra:Francci3_3865 GTP-binding protein TypA. (609 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.809
Afer_0577
KEGG: oih:OB1441 hypothetical protein.
       0.683
rpmI
TIGRFAM: ribosomal protein L35; PFAM: ribosomal protein L35; KEGG: dau:Daud_1382 ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
  
    0.652
Afer_0286
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicases; helicase domain protein; KEGG: pac:PPA1787 ATP-dependent RNA helicase.
 
  
 0.639
rpsI
PFAM: ribosomal protein S9; KEGG: bsu:BSU01500 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
    0.612
rplA
Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
  
 0.610
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
    0.596
rimP
Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
  
  
 0.567
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
  
 0.565
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.558
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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