Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0586PFAM: MMPL domain protein; KEGG: sco:SCO5084 hypothetical protein. (778 aa)    
Predicted Functional Partners:
Afer_0587
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: pla:Plav_2620 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
     
 0.776
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.769
Afer_0588
PFAM: AMP-dependent synthetase and ligase; KEGG: fra:Francci3_2165 AMP-dependent synthetase and ligase.
   
 
 0.746
acpP-2
Phosphopantetheine-binding; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
    
 
 0.589
Afer_0087
PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: rxy:Rxyl_0021 serine/threonine protein kinase.
    
 
 0.511
Afer_0088
PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: kra:Krad_0072 protein kinase.
    
 
 0.511
Afer_1553
PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: ace:Acel_0986 serine/threonine protein kinase.
    
 
 0.511
Afer_0583
Hypothetical protein; KEGG: art:Arth_2181 transcriptional regulator-like protein.
 
     0.502
Afer_1986
PFAM: Ig family protein; KEGG: sus:Acid_0470 Ig family protein.
  
     0.495
Afer_0471
PFAM: Polyprenyl synthetase; KEGG: saq:Sare_3478 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
   
 0.491
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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