STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0590PFAM: protein of unknown function DUF121; KEGG: nfa:nfa42070 hypothetical protein. (206 aa)    
Predicted Functional Partners:
Afer_0741
TIGRFAM: LPPG domain protein containing protein; PFAM: protein of unknown function UPF0052 and CofD; KEGG: rxy:Rxyl_0958 LPPG:Fo 2-phospho-L-lactate transferase.
 
  
 0.984
Afer_0589
PFAM: LmbE family protein; KEGG: rca:Rcas_1145 LmbE family protein.
       0.773
Afer_0740
TIGRFAM: F420-dependent oxidoreductase; PFAM: protein of unknown function DUF129; KEGG: sco:SCO3037 F420-0--gamma-glutamyl ligase.
 
   
 0.760
Afer_0900
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: rxy:Rxyl_0975 FO synthase.
 
   
 0.673
Afer_0791
PFAM: Luciferase-like monooxygenase; KEGG: fal:FRAAL2800 hypothetical protein.
 
   
 0.672
Afer_0591
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.584
Afer_0258
KEGG: cef:CE1107 hypothetical protein.
  
     0.574
Afer_0919
Thymidylate synthase complementing protein ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
  
     0.536
Afer_0860
PFAM: Luciferase-like monooxygenase; KEGG: sco:SCO6786 oxidoreductase.
 
   
 0.533
Afer_0797
PFAM: acyl-ACP thioesterase; KEGG: nfa:nfa20140 hypothetical protein.
  
     0.434
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.