Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0608PFAM: peptidase C26; glutamine amidotransferase class-I; KEGG: mta:Moth_2164 peptidase C26. (237 aa)    
Predicted Functional Partners:
Afer_0609
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: tbd:Tbd_0690 HAD family hydrolase.
       0.781
Afer_0274
Transcriptional regulator, XRE family; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: art:Arth_0847 transcriptional regulator, XRE family with cupin sensor.
 
  
 0.660
Afer_0607
PFAM: GCN5-related N-acetyltransferase; KEGG: art:Arth_1175 GCN5-related N- acetyltransferase.
       0.561
Afer_1967
PFAM: glutamine synthetase catalytic region; KEGG: fra:Francci3_0315 L-glutamine synthetase.
 
  
 0.511
Afer_0610
Putative phage repressor; PFAM: peptidase S24 and S26 domain protein; KEGG: sde:Sde_2043 folylpolyglutamate synthetase.
       0.498
Afer_0606
KEGG: fra:Francci3_2206 hypothetical protein.
       0.432
Afer_0242
PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sat:SYN_01628 glutamine synthetase.
  
  
 0.411
Afer_0243
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: fre:Franean1_1770 glutamine synthetase, type I.
  
  
 0.411
Afer_0871
PFAM: glutamine synthetase catalytic region; KEGG: blj:BLD_0159 glutamine synthetase.
  
  
 0.411
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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