STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0609TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: tbd:Tbd_0690 HAD family hydrolase. (249 aa)    
Predicted Functional Partners:
Afer_0608
PFAM: peptidase C26; glutamine amidotransferase class-I; KEGG: mta:Moth_2164 peptidase C26.
       0.781
tadA
CMP/dCMP deaminase zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
      0.730
Afer_0723
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
    0.572
Afer_0607
PFAM: GCN5-related N-acetyltransferase; KEGG: art:Arth_1175 GCN5-related N- acetyltransferase.
       0.566
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.550
Afer_0120
PFAM: ribulose bisphosphate carboxylase small chain; KEGG: afe:Lferr_1388 ribulose-bisphosphate carboxylase.
 
   
 0.506
Afer_0610
Putative phage repressor; PFAM: peptidase S24 and S26 domain protein; KEGG: sde:Sde_2043 folylpolyglutamate synthetase.
  
    0.505
Afer_0119
PFAM: ribulose bisphosphate carboxylase large chain; Ribulose bisphosphate carboxylase, large subunit- like; KEGG: afe:Lferr_1389 ribulose-bisphosphate carboxylase; Belongs to the RuBisCO large chain family.
 
     0.470
Afer_0606
KEGG: fra:Francci3_2206 hypothetical protein.
  
    0.432
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.